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A general theme in aluminium toxicity is accelerated cell death. Mechanisms have
been described to account for this phenomenon from both acute and chronic aluminium
challenges in which aluminium associations with both extracellular surfaces and
intracellular ligands are implicated [133]. Most concern about aluminium toxicity
refers to its derived neurodegenerative disorders, with a special mention to the
potential implication of aluminium in the pathogenesis of AD